Numerical Prediction of Particle Dynamics Within a Cytometer. Application to Counting and Sizing by Impendance Measurement

D. Isèbe[1]
[1]HORIBA Medical, Montpellier, France
Published in 2013

This paper describes how to numerically tackle the problem of counting and sizing particles by impedance measurement in an orifice–electrode system. The model simulate the particle dynamics submitted to strong hydrodynamic stresses through a microorifice and compute the voltage pulses generated by the modification of the inner dielectric medium. This FSI problem is solved on a moving mesh by an ALE method. To control the solution, the mesh deformation stops when the quality becomes lower than a specified value and an automatic remeshing is then performed. This approach gives important information about particles size distribution and allows to quantify the role of trajectory and orientation of particles on the size measurement.