See How Multiphysics Simulation Is Used in Research and Development

Engineers, researchers, and scientists across industries use multiphysics simulation to research and develop innovative product designs and processes. Find inspiration in technical papers and presentations they have presented at the COMSOL Conference. Browse the selection below or use the Quick Search tool to find a specific presentation or filter by application area.


View the COMSOL Conference 2023 Collection

Bioscience and Bioengineeringx

Geometry Optimization of Enzymatic Electrochemical Glucose Sensor new

Nachiket Aashish Gokhale1, Kartik Jain1, Siddhartha Panda1
1Indian Institute of Technology Kanpur

Diabetes is a metabolic disorder that is on a rising tide. Diabetic patients must regularly monitor their blood glucose levels. One method for designing such a device is using electrochemical principles, specifically amperometry to determine glucose concentration. It is essential to ... Read More

Designing and Fabrication of Lab On a Chip for the Therapeutic Drug Monitoring of Erlotinib new

Vivina Puthur 1, Sreema M.1, Jiya K. J.1, Ripsymol Toby1, Athira C.S.1, Arun Warrier1, Pooja Das M.1, Dr. Dhanya Gangadharan1, Dr. Jeethu Raveendran2
1Department of Biotechnology, Sahrdaya College of Engineering and Technology
2Department of Biomedical Engineering, Sahrdaya College of Engineering and Technology

Microfluidics and Biosensors are two principal fields that paved the way for the inception of Lab-on-a-chip (LOC) which provides early and cost-effective disease detection, from monitoring to treatment. LOC is a device that uses very small amounts of fluid on a microchip to do certain ... Read More

Analysis of cancer cell behaviour using sub-THz excitation in COMSOL Multiphysics new

Monodipa Sarkar (2)1, Aayushi Sinha (1)2, Niraj Kumar (3)3
1Vacuum Electron Devices Design Group, Academy of Innovative and Scientific Research (AcSIR), Ghaziabad, India,2001002
2 Amity Institute of Biotechnology (Autonomous) , Amity University Noida, India, 201303
3Vacuum Electron Devices Design Group(CSIR-CEERI, Pilani) , Academy of Innovation and Scientific Research (AcSIR) Ghaziabad, India,2001002

In this paper, analysis of cancer cell using Sub-THz technology have been studied. Sub-THz technique for cancer detection is a much reliable and safer technique as compared to conventional methods [1,2]. To study the behavior of cancer cells and normal cells using Sub-THz technology, a ... Read More

Electrochemical Impedance Spectroscopy in Carbonate Buffered Media for Biosensing Applications

Y. Abbas1, A.R.M. Verschueren1, J.F.M. Oudenhoven1
1imec at Holst Centre, 5656 AE Eindhoven, The Netherlands

Electrochemical Impedance Spectroscopy (EIS) is a technique commonly used to investigate the properties of the electrode surface and the bulk electrolyte in an electrochemical cell [1]. An AC excitation signal is applied with a frequency range, typically from 0.01 Hz to 1 MHz, and the ... Read More

3-D Modeling of Stresses and Strains in Accessory Carpal Bone Under Maximum Compressive Loading

Thomas Reuter1, Jennifer Gernhardt2, Christian Rutter1, Christoph Lischer2
1Institut Chemnitzer Maschinen- und Anlagenbau e.V., 09117 Chemnitz, Germany
2Klinik für Pferde Allgemeine Chirurgie und Radiologie Freie Universität Berlin, 14163 Berlin, Germany

When treating fractures of the accessory carpal bones in horses, it is important to understand the forces that implants (screws and plates) must withstand. The etiology of the fracture is not fully understood, but their high incidence during exercise suggests a relation to biomechanical ... Read More

Electrothermoplasmonic Flow in Gold Nanoparticle Suspensions

Emilio Ruiz-Reina1, Carlos David Gónzalez-Gómez1, Raúl A. Rica2
1University of Málaga, Málaga, Spain
2University of Granada, Granada, Spain

Efficient mixing and pumping of liquids at the microscale is a technology that is still to be optimized. The combination of an AC electric field with a small temperature gradient leads to a strong electrothermal flow that can be used for multiple purposes. Combining simulations and ... Read More

Modeling of Oxygen Metabolism in 3D Cell Constructs with LiveLink™ for MATLAB®

P. Mancini1, F. Fontana2, E. Botte1, F. Biagini2, C. Magliaro1, A. Ahluwalia1
1Research Center “E. Piaggio”, University of Pisa, Pisa, Italy - Department of Information Engineering, University of Pisa, Pisa, Italy
2Research Center “E. Piaggio”, University of Pisa, Pisa, Italy

In silico models can be exploited to predict cellular dynamics, such as resource uptake, migration and proliferation. Continuum modelling strategies such as finite element (FE) simulations are amongst the most common, but cannot exhaustively describe the metabolic consumption of cells, ... Read More

Simulation of Bioreactor Flow Characteristics and Cell Cultivation

Amer Alameri1
1Technische Hochschule Mittelhessen, IBMT - Institute for Biomedical Engineering

Bioreactors play a critical role in cultivating biological cells for various applications, such as pharmaceutical production and tissue engineering. Optimizing the cultivation process requires a deep understanding of the flow characteristics within the bioreactor medium. In this study, ... Read More

Multiphysics Inertial Particle Focusing (IFP) Model Validated for 3D Microfluidic Geometries

G. Spinola Durante1, D. Bayat1
1CSEM SA (CH)

Inertial focusing of particles in a fluid flow is a physical effect induced by inertial forces already happening at the micro-fluidic scale. COMSOL Multiphysics® has provided an implementation of the drag and lift forces to compute this effect for a constant parallel-wall fluid channel ... Read More

Modeling the Indoor Removal of Volatile Organic Compounds (VOCs) by Botanical Biofiltration

Allan A. Alvarado-Alvarado1, S. Denys1
1Sustainable Energy, Air and Water Technology Research Group (DuEL), Department of Bioscience Engineering, University of Antwerp, Antwerp, Belgium

Historically, indoor air quality (IAQ) has received less attention than outdoors, although people spend >90% of their time in the indoor environment. A major group of indoor air pollutants is volatile organic compounds (VOCs), which are detrimental to human health even at low ... Read More

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