See How Multiphysics Simulation Is Used in Research and Development

Aqui você encontrará apresentações realizadas nas Conferências de Usuários COMSOL de todo o mundo. As apresentações englobam pesquisas e produtos inovadores feitas por engenheiros e cientistas usando o COMSOL Multiphysics. Os tópicos abrangem uma grande gama de indústrias e aplicações, como elétrica, mecânica, escoamento e química. Use a função de busca "Quick Search" para encontrar apresentações na sua área de interesse.
View the COMSOL Conference 2018 Collection
Bioscience and Bioengineeringx

Computational Modeling to Study the Treatment of Cardiac Arrhythmias using Radiofrequency Ablation

A. González-Suárez[1], M. Trujillo[2], J. Koruth[3], A. D'Avila[3], E. Berjano[1]
[1]Biomedical Synergy, Electronic Engineering Department,Universitat Politècnica de Valencia, Valencia, Spain
[2]Instituto Universitario de Matemática Pura y Aplicada, Universitat Politècnica de Valencia, Valencia, Spain
[3]Helmsley Cardiac Electrophysiology Center, Mt SinaiMedicalCenter and School of Medicine, New York, NY, USA

Previous studies proposed using bipolar radiofrequency ablation across two catheters placed on opposing surfaces of the ventricular wall to create transmural lesions. 2D and 3D models were built and solved with COMSOL Multiphysics software. With these models, it was possible to study the ... Saiba Mais

基于 DTI 纤维追踪和有限元力学模型的脑损伤轴突纤维损伤研究

李娜 [1], 李江红 [2]
[1] 中南大学湘雅三医院,长沙,湖南,中国
[2] 中车集团南车研究所,株洲,湖南,中国

研究头部损伤机理是对运动撞击中脑损伤进行预测的有效手段。数学模型是分析损伤实验数据、预测人员碰撞损伤程度的唯一方法,但现有的头部损伤有限元模型基于尸体实验数据,且忽略脑组织结构的各向异性。本项目旨在提出并实现一种以损伤生物力学为基础、结合磁共振扫描 DTI 的轴突走向信息的有限元力学模型。提取脑外伤前的弥散张量成像信息,实现深入到轴突水平有限元力学模型的建立,在有限元模拟中采用非线性超弹性力学模型,并植入 NSGAII 最优化方法对有限元模型的材料参数进行优化,从而提高模型的稳定性和计算精度;将计算预测结果与损伤后 DTI 的 FA 值所表现的轴突断裂情况进行验证, ... Saiba Mais

Computational Modeling of Electrode with Saline Irrigation for Radiofrequency Cardiac Ablation

J. H. Moon [1], J. W. Ahn [1], Y. J. Kim [1], S. A. Lee [1], H. C. Jung [1], S. H. Lee [1],
[1] Osong medical innovation foundation, medical device development center, Cheongju-Si, South Korea

Radiofrequency catheter ablation is the interventional therapy that be employed to eliminate cardiac tissue caused by arrhythmias. During radiofrequency catheter ablation, the formation of thrombus can occur at electrode tip if the temperature of interface between electrode tip and ... Saiba Mais

Modeling of snRNP Motion in the Nucleoplasm

M. Blaziková[1], J. Malínský[2], D. Stanek[3], and P. Herman[1]
[1]Faculty of Mathematics and Physics, Charles University, Prague, Czech Republic
[2]Institute of Experimental Medicine, Prague, Czech Republic
[3]Institute of Molecular Genetics, Prague, Czech Republic

Small nuclear ribonucleoprotein particles (snRNPs) are essential supramolecular complexes involved in pre-mRNA splicing, the process of post-transcriptional RNA modifications. The particles undergo complex assembly steps inside the cell nucleus in a highly dynamic compartment called the ... Saiba Mais

Multiphysics Modeling of Cellular Arrays Using Periodic Minimal Surfaces – A Drug and Gene Delivery Application

J.I. Rey, A.J. Llewellyn, R.J. Connolly, J.P. Jimenez, A.M. Hoff, and R.A. Gilbert
University of South Florida, Tampa, FL, USA

Minimal surfaces are found in nature from crystalline structures to biological nano and micro structures such as biomembranes, and osseous formations in sea urchin. An application to electrically mediated drug and gene delivery is presented. Periodic level surfaces which approximate ... Saiba Mais

Energy Harvesting from Variation in Blood Pressure through Deformation of Arterial Wall using Electro-magneto-hydrodynamics

A. Pfenniger[1], V.M. Koch[2], A. Stahel[2], and R. Vogel[1]
[1]ARTORG Cardiovascular Engineering, University of Bern, Bern, Switzerland
[2]Bern University of Applied Sciences, Engineering and Information Technology, Biel, Switzerland

The present project aims at modelling a generator that harvests energy from the variation in blood pressure by exploiting the motion of the arterial wall between the diastolic and systolic phase of the cardiac cycle. The concept is to use a highly electrically conductive fluid, which is ... Saiba Mais

Optimizing Performance of Equipment for Thermostimulation of Muscle Tissue using COMSOL Multiphysics

J. Kocbach[1], K. Folgerø[1], L. Mohn[2], O. Brix[3]
[1]Christian Michelsen Research, Bergen, Norway
[2]Luzmon Norway, Bergen, Norway
[3]Michelsen Medical, Bergen, Norway

The design challenge for thermostimulation equipment is to get a combination of high electric field strength and high temperature within the muscle tissue without causing pain or skin burns. In the present work, COMSOL Multiphysics is used to simulate the temperature distribution and ... Saiba Mais

Finite Element Analysis of Defibrillation Current Density in Pregnant Women

A. Jeremic[1], E. Khosrowshahli[1]
[1]McMaster University, Hamilton, ON, Canada

Although resuscitation during pregnancy is relatively uncommon and rarely causes death, they have a particularly large impact in terms of the mortality of the unborn child and long-term effects on families and society as whole. In this paper, we present a new 3D finite element model of a ... Saiba Mais

Design and Optimization of Cholesterol Biosensor

N. M. Sundaram[1], M. Alagappan[1]
[1]PSG College of Technology Coimbatore, Tamil Nadu, India

Cholesterol is an essential lipid for human body. The desired total plasma cholesterol for an individual is less than 5.2 mM (200 mg/dL) and it poses a potential health threat when the level is greater than 6.2 mM (240 mg/dL) [1]. Excessive plasma cholesterol causes poor cardiovascular ... Saiba Mais

Modeling of Nerve Stimulation Thresholds and Their Dependence on Electrical Impedance with COMSOL

P. Krastev[1], and B. Tracey[1]
[1]Neurometrix, Inc., Waltham, Massachusetts, USA

Nerve localization is important for applications in regional anesthesia. Localization is achieved by stimulating the nerve with an electric field produced by a current from a needle inserted into the body of the patient, close to the target nerve.  Modeling of the electric field in ... Saiba Mais