See How Multiphysics Simulation Is Used in Research and Development

Engineers, researchers, and scientists across industries use multiphysics simulation to research and develop innovative product designs and processes. Find inspiration in technical papers and presentations they have presented at the COMSOL Conference. Browse the selection below or use the Quick Search tool to find a specific presentation or filter by application area.


View the COMSOL Conference 2023 Collection

Bioscience and Bioengineeringx

From Music to Non-Invasive Therapies via COMSOL Multiphysics® Models

E. Lacatus[1], G. C. Alecu[2], A. Tudor[2], M. A. Sopronyi[3]
[1]Polytechnic University of Bucharest, Bucharest, Romania
[2]Student-Polytechnic University of Bucharest, Bucharest, Romania
[3]INFLPR -National Institute for Laser Plasma and Radiation Physics, Bucharest, Romania

Vibration and music therapies are non-invasive treatments having effective results although their basics are still disputed. By the application of COMSOL Multiphysics® software for modeling and analysis, some of the nonlinear physical phenomena laying on these applications may be ... Read More

Determination of the Mechanical Properties in the Avian Middle Ear by Inverse Analysis

P. Muyshondt[1], J. Soons[1], D. de Greef[1], J. Peacock[1], J. Dirckx[1]
[1]University of Antwerp, Antwerp, Belgium

The middle ear of birds is a fascinating mechanical system, as it contains only one bony ossicle, compared to three in mammals, yet its auditory performance is not substantially worse. Its design resembles some currently used middle ear prostheses, so the understanding of its working ... Read More

Analysis to Determine Optimum Strain Gauge Locations for SENSEWHEEL

T. Suzuki[1], C. Holloway[1], S. Taylor[1]
[1]University College London, London, UK

Manual wheelchair users suffer shoulder pain and injury in the long term because of unconscious overuse. The ‘SENSEWHEEL’, which interposes three identical load cells between pushrim and rear wheel, measures the three components of pushing force Fx, Fy and Fz, and axial torque Tx ... Read More

Simulating Organogenesis in COMSOL Multiphysics®: Image-Based Modeling

D. Iber[1,3], Z. Karimaddini[1,3], E. Unal[1,2], D. Menshykau[1,3]
[1]D-BSSE, ETH Zurich, Basel, Switzerland
[2]DBM University of Basel, Basel, Switzerland
[3]Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland

Mathematical Modeling has a long history in developmental biology. Advances in experimental techniques and computational algorithms now permit the development of increasingly more realistic models of organogenesis. In particular, 3D geometries of developing organs have recently become ... Read More

Simulations of Lateral Flow and Vertical Flow Microarray Assays for Point of Care Diagnostics

G. E. Svedberg[1], L. Lama[1], J. Gantelius[1]
[1]Science for Life Laboratory, Stockholm, Sweden

Paper based lateral flow assays are widely used as point of care devices for disease diagnostics due to their low cost, short run time and ease of use. Binder molecules specific for certain molecular biomarkers of interest are typically deposited as dots or lines on paper strips, ... Read More

Modeling Bioclogging Effects in Constructed Wetlands for Wastewater Treatment

R. Samso[1], N. Forquet[2], P. Molle[2], J. Garcia[1]
[1]Department of Hydraulic, Maritime and Environmental Engineering, Universitat Politècnica de Catalunya-BarcelonaTech, Barcelona, Spain
[2]IRSTEA, Freshwater Systems, Ecology and Pollution Research Unit, Villeurbanne, France

Horizontal-Flow Constructed Wetlands (HFCWs) are a particular type of biofilter, and as such they rely mostly on the activity of bacterial communities to treat wastewater. Bacterial growth in HFCWs induces dramatic changes in its hydraulic and hydrodynamic behaviour (bioclogging), which ... Read More

Fresh Produce Safety During Hydrocooling: An Engineering Model

A. Warning[1], A. K. Datta[1]
[1]Department of Biological & Environmental Engineering, Cornell University, Ithaca, NY, USA

Hydrocooling is the process by which warm produce is chilled with water. The chilling of warm produce generates a negative pressure differential between the produce (warm) and (cold) water due to the condensation of water vapor inside the produce which forms a vacuum and can pull in ... Read More

Simulation of Cellular Traction Force Based Deflection of PDMS Micropillars

J. Wala[1], D. Maji[1], S. Dhara[1], S. Das[1]
[1]Indian Institute of Technology Kharagpur, Kharagpur, West Bengal, India

Cells are complex entities which not only passively sense external stimuli (viz. chemical, optical or mechanical) but also interact with extracellular matrix (ECM) by regulating cellular behavior such as growth, proliferation, migration, etc. Monitoring cell growth and migration of ... Read More

Microwave Exposure System for In Vitro and In Vivo Studies

C. Nadovich[1, 2], W. D. Jemison[2], J. A. Stoute[3], C. Spadafora[4]
[1]Lafayette College, Easton, PA, USA
[2]Clarkson University, Potsdam, NY, USA
[3]Pennsylvania State University, Hershey, PA, USA
[4]INDICASAT AIP, Ciudad del Saber, Panama

A computer controlled microwave exposure system and specialized applicators were constructed for the purpose of facilitating accurate observations of microwave radiation effects on uninfected and infected biological tissue in vitro and in vivo under different electromagnetic modalities ... Read More

Multiscale Model of Human Pathogen Growth on Fresh Produce

A. Warning[1], A. K. Datta[1]
[1]Department of Biological & Environmental Engineering, Cornell University, Ithaca, NY, USA

Predictive food microbiology currently first requires experimental data for growth on fresh produce and then fitting an empirical or semi-empirical model to the data, making extrapolation to other conditions (temperature, type of produce) difficult. Herein, we develop a mechanistic ... Read More